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Daiichi Sankyo Company –
Oncology Drug Pipeline Insights – June 2021

Oncology New Molecules Development Strategy

Team OmicsX by Team OmicsX
June 14, 2021 - Updated On May 30, 2022
in Big Pharma, Onco Pipeline Insights, Oncology
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Daiichi Sankyo is the second largest pharma company in Japan, developing small molecules & biologics for various diseases and was came into existence in 2005, through the merger of Sankyo Co., Ltd. and Daiichi Pharmaceutical Co., Ltd.

Global Oncology Intelligence Global Oncology Intelligence
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1. Daiichi Sankyo Major Oncology Drug Approvals

  • 1. Daiichi Sankyo Major Oncology Drug Approvals
  • 2. Daiichi Sankyo Active Clinical Stage Oncology Pipeline (12 Active Molecules)
  • In Jan 2021, Daiichi Sankyo files for New Drug Application (NDA) to Japan’s Ministry of Health, Labour and Welfare (MHLW) for teserpaturev (G47∆), an oncolytic virus, for the treatment of patients with malignant glioma.
  • In Jan 2021, the US FDA approved fam-trastuzumab deruxtecan-nxki (ENHERTU®, Daiichi Sankyo) for adult patients with locally advanced or metastatic HER2-positive gastric or gastroesophageal (GEJ) adenocarcinoma who have received a prior trastuzumab-based regimen.
  • In Dec 2020, the US FDA granted accelerated approval to fam-trastuzumab deruxtecan-nxki (ENHERTU®, Daiichi Sankyo) for patients with Unresistable or metastatic HER2-positive breast cancer who have received two or more prior anti-HER2-based regimens in the metastatic setting.
  • In Aug 2019, the US FDA approved Turalio (pexidartinib), an oral small molecule tyrosine kinase inhibitor (TKI) indicated as a treatment for symptomatic tenosynovial giant cell tumor (TGCT) associated with severe morbidity or functional limitations and not amenable to improvement with surgery.
  • In June 2019, Japan’s Ministry of Health, Labor and Welfare (MHLW) approved FLT3 Inhibitor VANFLYTA® (quizartinib) in Japan for the Treatment of Patients with Relapsed/Refractory FLT3-ITD acute myeloid leukemia (AML).
  • Vemurafenib/Zelboraf™ (developed by Plexxikon in collaboration with Roche) is FDA approved for the treatment of Unresistable or metastatic melanoma (for further details see Plexxikon).
Jump to section

1. Daiichi Sankyo Major Oncology Drug Approvals

  • 1. Daiichi Sankyo Major Oncology Drug Approvals
  • 2. Daiichi Sankyo Active Clinical Stage Oncology Pipeline (12 Active Molecules)
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